The SoHo-ification of New York’s NoMad neighborhood continues with the arrival of a boutique hotel by the Chicago-born brand that became a phenomenon in—you guessed it—SoHo. It joins an already impressive clique of hotels (the NoMad, Ace, the Edition, and Arlo are all nearby) in the formerly forlorn blocks between the Flatiron and Empire State Buildings, turning the area into a new nexus of cool. James’s newest outpost is more ambitious than its predecessors, with nearly as many rooms and suites, 344, as the SoHo and Chicago locations combined. Designed by Danish-born Thomas Juul-Hansen, who conceived chef Jean-Georges Vongerichten’s private home and several of his restaurants, its highlights include grated-brass minibars and hand-carved bathroom vanities. The ground floor houses an outpost of LDV Hospitality’s hit restaurant Scarpetta and the James Club, the place to find on-loan iPads and confections from local bakeries. Works by New York artists such as Justine Hill and Adrian Coleman are displayed throughout the public spaces along with music and architecture tomes celebrating NoMad’s roots. Small vestiges of what the fast-changing neighborhood once was.